As for the eight common genes screened out in all four datasets, CEACAM1, GK, PFKFB3, and TNFAIP6 emerged repeatedly in the S. aureus group, but CEACAM1, IL18RAP, LILRA5, PFKFB3, PSTPIP2, and SOCS3 emerged in the E. coli infection. This evidence concerns the gene IL18RAP and escherichia coli infection.