IFNG and melanoma: Assessing RNA expression of IFN-gamma related genes using a six-gene signature (CXCL9, CXCL10, IDO1, IFNG, HLA-DRA and STAT1) identified in a melanoma cohort in the KEYNOTE-001 study [66], showed that all six IFN-gamma related genes had significantly higher mean expression values in pembrolizumab-responders compared to non-responders [65].