CDKN2A and head and neck squamous cell carcinoma: A recent study suggested that HNSCC associated with HPV genotypes other than HPV-16 have inferior survival, and that determination of HPV genotypes in HNSCC could provide a more robust risk stratification than p16 IHC findings or HPV-16 detection alone, especially in the era of treatment de-intensification for HPV-associated HNSCC [17].