When these variables were included in the multivariate analysis using the forward LR method, high-level BIRC5, advanced TNM stage, and person neoplasm cancer status with tumor were the risk factors that significantly contributed to worse OS in TN adenocarcinoma patients (P = 0.015, P = 0.049, and P < 0.001, respectively, Table 2). Here, BIRC5 is linked to cancer.