pGP motif binds to (C–X–C motif) receptors and is thus associated with neutrophil attraction in inflamed tissues.39 In addition, protein phosphatase 1 regulatory subunit 3A, which is considered as a tumour suppressing molecule was identified with decreased abundance.40 Overall, the observations at the urinary peptides of the patients with Sig PCa, depict features of cancer progression and tumour related inflammation. Here, PPP1R3A is linked to cancer.