We observed that in such conditions cancer cells differentially activated and thrived on endogenous lipid synthesis pathways.13 As expected, the expression and activity of SCD1 were also elevated.50 Therapeutic inhibition of SCD1 has been shown to efficiently reduce cancer cell proliferation by selectively depleting MUFAs.60–62 The inhibition of SCD1 increases the susceptibility of cancer cells towards chemotherapeutic drugs and metabolic inhibitors. Here, SCD is linked to cancer.