This suggests the mechanism by which the SLE-risk haplotype is affecting disease risk is through candidate gene CXorf21. To refine this analysis in terms of cellular expression, we used data from Blueprint Epigenome (RNA-sequencing) and BioGPS (microarray) to show that within immune cell types, the expression of CXorf21 is largely restricted to monocytes, neutrophils and B cells (Supplementary Fig. 9). The gene discussed is TASL; the disease is systemic lupus erythematosus.