In addition, two associations with T2D-ESKD, rs4807299 (P = 3.21 × 10−8, OR = 1.67, EAF = 0.05) located in GNG7 and rs72858591 (P = 4.54 × 10−8, OR = 1.43, EAF = 0.10) located in RND3/RBM43 were identified (Fig. 1a). This evidence concerns the gene GNG7 and type 2 diabetes mellitus.