The meta-analysis combining cases with T2D-ESKD and non-diabetic ESKD identified two novel genome-wide significant loci associated with all-cause ESKD in addition to APOL1; rs77113398 near EFNB2 (P = 9.84 × 10−9; baseline model) and rs373971520 in GNG7 (2.17 × 10−8; APOL1-negative model). The gene discussed is GNG7; the disease is type 2 diabetes mellitus.