APOL1 and type 2 diabetes mellitus: The most significant association with T2D-ESKD (OR = 0.77, P = 1.42 × 10−10) and all-cause ESKD (OR = 0.69, P = 1.96 × 10−25) in the baseline model was an intronic variant rs9622363 in the APOL1 region associated with non-diabetic kidney disease in individuals with African ancestry.