MIIP and posterior cortical atrophy: In addition, the ratio of colony formation in LNCaP-MIIP and C4–2-MIIP were much lower than those in control PCa cell (LNCaP: 33.27 ± 1.03% vs 19.53 ± 2.73%,*p<0.05; C4–2:72.33 ± 8.06% vs 51.53 ± 2.91%,*p<0.05, Fig. 1d).