MIIP is a newly identified tumor suppressor in many different types of cancer, including glioma, lung cancer, colon cancer, endometrial carcinoma, pancreatic cancer and others [18–20, 22, 24, 25], yet its role in prostate cancer has not been reported and its biological function and the relevant mechanism is far from clarified. The gene discussed is MIIP; the disease is malignant colon neoplasm.