SDHB and renal cell carcinoma: The histological features of both neoplasms were similar between themselves and to those previously reported for SDH-deficient RCC and were characterized by uniform tumor cells arranged in nests or solid sheets with a characteristic granular flocculent cytoplasm and cells with cytoplasmic pale inclusions which were vacuolated or contained eosinophilic fluid-like material [3] (Figs. 1a-b and 2.a-b).