“Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis” (ATLANTIS) aimed at comparing apixaban and warfarin on TAVI for AS while “Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibrillation” (ENVISAGE-TAVI) compared another factor Xa inhibitor, Edoxaban, with standard of care in TAVI patient. The gene discussed is F10; the disease is aortic stenosis.