Killing of αvβ6-positive pancreatic (Figure 3A), breast (Figure 3B) or ovarian (Figure 3C) tumor cells and secretion of either IFN-γ (Figure 3D) or IL-2 (Figure 3E) was comparable after co-culture with A20-28z+ CAR T-cells, irrespective of whether they co-expressed an IL-8-responsive chemokine receptor or not. Here, CXCL8 is linked to neoplasm.