These 8 biomarkers were sTNFR-1, sTNFR-2, hsCRP, D-dimer, sCD27, IP-10, sCD14, and hyaluronan; of these, sCD14, sTNFR-2, hyaluronan, and IP-10 were most strongly associated with HIV infection. This evidence concerns the gene CXCL10 and HIV infectious disease.