Accordingly, the aromatase-encoding gene(CYP19A1) (Barceloset al., 2015; Hosseini et al., 2016), and thecyclooxygenase 2 (COX-2)-encoding gene (PTGS2) (Donabela et al., 2011)that may mediate CYP19A1 induction, seem to be both lower in CCof infertile women with endometriosis compared to infertile controls undergoingcontrolled ovarian stimulation for intracytoplasmic sperm injection (ICSI). The gene discussed is PTGS2; the disease is Infertility.