Among them, CO4, B2MG, and A1AG enable early detection of cancer according to Wu et al.10 LG3BP is overexpressed in the serum or tissue of patients with various types of and plays roles in cancer cell aggregation and metastasis.23, 24, 25 CSF1 has been reported to be expressed in brain metastases of lung cancer and breast cancer.26 NKG2‐D type II integral membrane protein (NKG2D) acts as an activating receptor for killer cells, providing therapeutic targets for the treatment of infectious diseases, cancer and autoimmune diseases.27 This evidence concerns the gene KLRK1 and cancer.