Experimental data performed in prostate epithelial cells supports the hypothesis that increased androgen levels in younger men may be directly related to the increase in TMPRSS2‐ERG expression,11 while a previous European‐based study reported accumulation of nonandrogen associated genomic alterations with patient and tumor age, dependent on TMPRSS2‐ERG status.12 The gene discussed is TMPRSS2; the disease is neoplasm.