CTNNA2 and ischemia: Four hours after ischemia onset, neocortical mRNA levels of all analyzed genes except VE-cadherin (Cdh5) were significantly down-regulated by about 50%, whereat the fold change ranged between 0.55 for α-catenin 2 (Ctnna2) and 0.38 for N-cadherin (Cdh2).