PECAM1 and ischemia: However, among the exemplarily selected BBB-associated platelet endothelial cell adhesion molecule 1 (Pecam1) and the ECM-related hyaluronan synthase 1 (Has1), the protein levels did not change significantly following ischemia while considering neocortical and striatal areas as well as the duration of ischemia, i.e., 4 and 24 h.