ROS contribute to atherosclerosis, also inducing the worsening of endothelial dysfunction, increasing the expression of adhesion molecules like intercellular adhesion molecule-1 (ICAM-1) and vascular adhesion molecule-1 (VCAM-1), and modulating the expression of different growth factors important in the proliferation of vascular smooth muscle cells (VSMCs) [68]. This evidence concerns the gene ICAM1 and atherosclerosis.