EGFR and Increased total eosinophil count: Accordingly, there was increased expression of Muc5ac, pro-Th2 and Th17 cytokine (e.g., Il13, Il33 and Il17a), increased BALF eosinophilia, as well as increased genes involved in epithelial repair responses in the lungs (e.g. Egfr and Tff2).