ADIPOQ and atrial fibrillation: However, the association between adiponectin and new-onset AF was significant in studies with mean follow-up duration over 10 years (five cohorts, HR = 1.22, 95% CI: 1.16–1.29, P<0.001), but not in that with a follow-up duration < 10 years (one cohort, HR = 0.95, 95% CI: 0.82–1.11, P= 0.51; P for subgroup difference =0.002; Table 3).