CD86 and neoplasm: Expression of the DC markers MHCII and CD86 on NCsh and CRIG-Ish tumor TIDCs was downregulated compared with the expression of both markers on splenic DCs, CRIG-Ish tumor TIDCs exhibiting significantly lower expression levels of MHCII and CD86 than those of NCsh tumor TIDCs (Fig. 5b, c and d, n = 6).