AGAP2 and hepatocellular carcinoma: Additionally, to determine the effect of AGAP2-AS1 on cell growth in vivo, we used the subcutaneous tumor model to confirm that AGAP2-AS1 overexpression significantly promoted tumor growth, while AGAP2-AS1 knockdown inhibited the tumor growth of HCC cells in mice (P < 0.05, Fig. 3c, Additional file 2: Figure S2).