Based on the above results, in this study we analyzed CpG methylation for three genes that appeared to be frequently mutated in PDAC, including PCDHGC5 and PCDHAC2 that had not been studied before for epigenetic modifications and PCDH10, whose promoter methylation had been previously suggested as a prognostic marker in other cancers [13]. Here, PCDHAC2 is linked to cancer.