EGFR and non-small cell lung carcinoma: For the pathway analysis, we adopted the KEGG category and found driver genes enrich in the Focal adhesion, Regulation of actin cytoskeleton, ErbB signaling pathway, MAPK signaling pathway, Non-small cell lung cancer, Chemokine signaling pathway, Calcium signaling pathway, Wnt signaling pathway etc. which are significant associated with lung cancer (see Additional file 2).