PRRT2 and diabetes mellitus: 2012) and in various cell types, PKC activation inhibits gap junction function (Suarez and Ballmer‐Hofer 2001; Thuringer 2004; Nimlamool et al. 2015). To begin to assess the putative role of PKC, we measured ΔVresponder/ΔVstimulator ratios in diabetic retinal microvessels exposed for >1 h to the broad‐spectrum PKC inhibitor, chelerythrine (1 μmol/L; Fig. 4A). Analysis of ΔVresponder/ΔVstimulator ratios showed that chelerythrine significantly lessened (P = 0.0022) the diabetes‐induced inhibition of axial transmission (Fig. 4B).