EXO1 and cancer: Nevertheless, the overexpression of EXO1 has also been reported in several other cancers associated with poor prognosis, which in part is related to increased DNA repair activity (Axelsen, Lotem, Sachs, & Domany, 2007; Dai et al., 2018; de Sousa et al., 2017; Muthuswami et al., 2013).