The magnitudes of hypokalemia in the WT and HCN2-Tg mice again did not differ significantly (Fig. 5c: WT, black bar, 2.6 ± 0.3 mM; HCN2-Tg, red bar, 2.4 ± 0.6 mM; n = 3). The gene discussed is HCN2; the disease is Hypokalemia.