As summarized in Table 3, the ECG parameters (RR, PQ, QT, and QTc) were significantly prolonged by hypokalemia in both WT and HCN2-Tg mice, although no significant difference was found between the ECG parameters of WT and HCN2-Tg mice irrespective of the hypokalemia. Here, HCN2 is linked to Hypokalemia.