PIK3CA and gastric cancer: In addition, Zhou suggested that the mechanism of miR203 was regulating the level of ataxia telangiectasia mutated kinase-mediated-Snail and E-cadherin11, and Hao suggested that it was inducing the overexpression of PIK3CA gene.17 Although these two scholars studied the role of miR203 from different angles, they both suggest that miR203 can suppress gastric cancers.