Those with tumor metastasis (p=0.001), larger tumor diameter(p=0.001), lower differentiation (p=0.000), lymphatic metastasis(p=0.001), deeper invasion (p=0.000), and higher TMN stage (p=0.000) presented with a significantly lower expression, but similarly as CD147 and D-dimer, it didn’t show a significant difference in patients with different pathological type (p=0.13), gender (p=0.93), and age (p=0.59) . The gene discussed is BSG; the disease is neoplasm.