HMGB1 and acute respiratory distress syndrome: Therefore, we investigated the effect of a mixture of factors (IL1B [20], interleukin 6 (IL6) [20,21], complement component 3a (C3a) [22–24], complement component 5a (C5a) [23], high mobility group box 1 (HMGB1) [25,26], thrombomodulin (THBD) [27,28], thrombopoietin (THPO) [29]), playing a role in the early phase of PT or acute respiratory distress syndrome (ARDS), on MSC.