When we assessed the relationship between eIF2α-P and clinicopathological characteristics of HER2+ patients, we found no significant correlation between eIF2α-P and age, tumor size, tumor grade, lymph node status, or lympho-vascular invasion, as well as no correlation between eIF2α-P and either estrogen receptor (ER) or progesterone receptor (PR) status. Here, ESR1 is linked to neoplasm.