The effect of PXS-S1C on cancer growth and metastasis in an immunocompetent mouse model was investigated by injection of LY2 to the tongue of syngeneic immunocompetent mice (Balb/c mice)20 followed by intraperitoneal injections of the LOXL2 inhibitor (10 and 30 mg/kg) three times a week as above, and mice were sacrificed after 6 weeks. This evidence concerns the gene LOXL2 and cancer.