It is very plausible that this effect was associated with the higher secretion levels of several agents known to support ovarian cancer cell progression by these cells, such as CCL2, CXCL8, CXCL12, ICAM-1, IL-6, HGF, PAI-1, uPA, TGF-β1, and VEGF [2]. Here, SERPINE1 is linked to ovarian carcinoma.