Comparative analysis of the secretome of the PMCs, which focused on 10 soluble mediators of cancer cell progression, revealed that the CM from A2780 cells up-regulated the secretion of CCL2, CXCL12, HGF, and TGF-β1; the CM from SKOV-3 cells stimulated the secretion of CCL2, CXCL8, CXCL12, HGF, ICAM-1, TGF-β1, and VEGF; the CM from OVCAR-3 cells stimulated the secretion of CCL2, CXCL12, HGF, ICAM-1, PAI-1, TGF-β1, and VEGF; and the CM from primary EOCs stimulated the secretion of CCL2, CXCL8, CXCL12, HGF, ICAM-1, IL-6, PAI-1, TGF-β1, uPA, and VEGF. The gene discussed is CXCL12; the disease is cancer.