PRL and Anxiety: Optogenetic inhibition of PVN (OTergic) to the PrL pathway significantly increased anxiety-like behavior (males: t(10) = 3.051, p<0.05, Figure 8L, Figure 8—source data 1; females: t(10) = 5.875, p<0.01, Figure 8M, Figure 8—source data 1).