ALB and diabetic kidney disease: Although ubiquinol can improve the endothelial dysfunction associated with the diabetic kidney disease (systolic blood pressure and urinary albumin) [150], and a trial with CoQ10 supplementation (1200 mg/day in dialysis patients) identified a reduction in a plasma indicator of oxidative stress (F2-isoprostane) [151], a meta-analysis failed to prove CoQ10 efficacy in avoiding the progression of diabetic kidney disease [152].