MYOM2 and neoplasm: Using oncolytic rhabdovirus vesicular stomatitis virus harboring a deletion in the M protein (VSV-Δ51) in the B16 melanoma model, Lemay et al. demonstrated that a prime and boost immunization strategy, seven days apart, with the VSV-Δ51 infected B16 tumor cells was able to completely protect 30% of the C57Bl/6 mice from a B16 subcutaneous tumor challenge.