LTBP4 and neuromuscular disease caused by qualitative or quantitative defects of dystrophin: The GWAS that was conducted by the UDP consortium in their severe dystrophinopathy cohort [63], in addition to identifying the regulatory SNP upstream of LTBP4 that was described above, identified a distinct association signal, corresponding to the SNPs rs2725797 and rs2624259, which are in close proximity and strong LD (R2 = 0.95) at 15q14.