Only one analogous literature reported a patient, who had undergone a TIPS procedure for PHT complicating cystic fibrosis 18 months previously, was found multiple SAAs located in the splenic parenchyma, and embolized with steel coils and embospheres microspheres.[11] In our report, the patient was admitted to emergency room with hemorrhage of oesophageal varices. The gene discussed is PCSK1N; the disease is esophageal varices.