AOPEP and breast cancer: In the apo landscape, the general structural features of the X-ray structures of BC-Inh1, BC-Inh2, APO, BC-SAM and TC (Figure 1) are recapitulated by a subset of macrostates (e.g. A6 for BC-Inh1; A10 for BC-Inh2; A12 for APO; A20 for BC-SAM; A22, A24 for TC, 6 of 24 macrostates, Figure 11).