Since CXCL5 is also reported as a biomarker for various T helper 17 cell-mediated autoimmune disorders (30–32), the high serum levels of CXCL5 might be correlated with the anti-tumor immune response of anti-PD1 antibody that could also induce autoimmune-like responses such as interstitial pneumonia, autoimmune-like colitis, and hepatitis (33). Here, PDCD1 is linked to hepatitis A virus infection.