In contrast, CD90 was also shown to exert tumor suppressor functions in several others cancers, as its downregulation is associated with poor prognosis, disease progression in ovarian adenocarcinoma (Gabra et al., 1996; Abeysinghe et al., 2003), neuroblastoma (Fiegel et al., 2008) and nasopharyngeal carcinoma predominantly observed in metastatic tumor cells in invaded lymph nodes (Lung et al., 2005). Here, THY1 is linked to cancer.