Furthermore, when we analysed additional markers of EMT olaparib (CDH1; TWIST; SNAI2; ZEB1; ZEB2) in AC(NST) tumours after a single dose of olaparib, we found a significant increase in the proportion of cells staining for TWIST, SNAI2, ZEB1 and ZEB2 (p = 0.033, p = 0.043, p = 0.033 and p = 0.014 respectively) (Figure 6E). This evidence concerns the gene TWIST1 and neoplasm.