Furthermore, we discovered that the expression of miR-25 was negatively connected with the levels of the PRDM16, Which involved in AML translocation [18]; CD97, an EGF-TM7 receptor [19]; IRAK1, which activates NF-κB pathways by the interaction with TRAF6 [20]; NFKB2, a pro-inflammatory response gene [21]; MYH9, which predicts unfavorable outcome of AML [22]; HDAC11, a epigenetic regulator. The gene discussed is NFKB2; the disease is acute myeloid leukemia.