Naïve CD4+ T (OR: 12.67, 95% CI 2.26–71.18, P = 0.004), memory CD4+ T (OR: 0.17, 95% CI 0.05–0.66, P = 0.010), memory CD8+ T (OR: 0.11, 95% CI 0.01–0.97, P = 0.047), and CD4+ naïve/memory ratio (OR: 8.50, 95% CI 1.90–38.14, P = 0.005) were independent predictors of tumor response to SBRT (Table 3). Here, CD8A is linked to neoplasm.