IL17A and psoriasis: Ingenuity Pathway Analysis (IPA) identified several top canonical pathways that were related to IL-17 signaling in a variety of cell types including the role of IL-17A in psoriasis, IL-17A signaling in fibroblasts, and differential regulation of cytokine production in intestinal epithelial cells by IL-17A and IL-17F (Figure S2A), suggesting HBE1 cells were IL-17 responsive and could be used to study signaling pathways mediated by IL-17.