ACE and Duchenne muscular dystrophy: Eplerenone, an aldosterone antagonist, which was used in combination with an ACE inhibitor or an angiotensin receptor blocker, was reported to elicit a slight deceleration of left ventricular circumferential strain decline assessed by CMR in a 12 month follow-up period in 20 DMD patients with preserved left ventricular function (mean age 14.5 years).