Accordingly, aberrant expression or dysregulation of protein kinases has been reported to be involved in different hallmarks of cancer including proliferation, survival, motility, metabolism, angiogenesis, resistance to standard treatments and immunotherapies [43] and evasion of antitumor immune responses [44], having been demonstrated in the pathophysiology of different malignancies including breast [43], colon, kidney or pancreas [41] (Figure 4). Here, WEE1 is linked to cancer.