According to KEGG pathway enrichment analysis, at least 50% of DNB genes are closely related to hematopoietic cell lineage, cytokine-cytokine receptor interaction, apoptosis, chronic myeloid leukemia MAPK signaling pathway, PI3K-Akt signaling pathway and other gene pathways. This evidence concerns the gene AKT1 and chronic myelogenous leukemia, BCR-ABL1 positive.