On the other hand, however, abundantly expressed HSP in most of cancer cells promote their growth and survival and it has been proved that pharmacological downregulation of HSP expression as well as blockage of their chaperone activity resulted in tumor regression (Ciocca et al. 2012; Li et al. 2013; Tukaj and Węgrzyn 2016). The gene discussed is HSP90B2P; the disease is neoplasm.