CCND1 and lung carcinoma: The levels of cyclin D1, which is a protein encoded by CCND1 and is necessary to regulate the cell cycle from G1 to S and promote cell differentiation and apoptosis [112, 113], decreased in H460 lung cancer cells under SMG using a RPM [23], MDA-MB-231 and MCF-7 [40, 41] breast cancer cells using a RPM and RCCS-HARV, leading to cell aggregation in the S and G2/M phase.