miR-203 also plays a role in HCC development and progression [17], enhances apoptosis of HCC cells by regulating EZH2 (enhancer of zeste, drosophila, homolog 2) and BMI-1 (leukemia viral bmi-1 oncogene, mouse, homolog of) [18], and inhibits HCC cell proliferation by targeting SURVIVIN [19], RASAL2 (ras protein activator-like 2) [20], ADAM9 oncogene and the HULC pro-tumorigenic long non-coding RNA [21] and the long non-coding RNA DLX6-AS1 and MMP2 (matrix metalloproteinase 2) [22]. Here, BMI1 is linked to hepatocellular carcinoma.