Previous work in our laboratory identified and analyzed HCC subgroups with poorer prognosis (survival < 3 years after partial liver resection; HCCP) and better prognosis (survival > 3 years; HCCB) showing lower decrease in MAT1A expression and lower increase in MAT2A expression in HCCB [7, 8]. The gene discussed is MAT2A; the disease is hepatocellular carcinoma.