IL1B and Cognitive impairment: In turn, a four-week swimming training attenuated motor and cognitive impairment, prevented the increase in reactive oxygen species (ROS) and interleukin 1 beta (IL-1β) levels, glutathione S-transferase (GST), and glutathione reductase (GR) activity, prevented the inhibition of glutathione peroxidase (GPx) activity, restored the levels of DA and its metabolites in the striatum of mice administered with 6-OHDA [21].